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Tuesday, March 28, 2023

Research Indicates Environment is Unlikely to Affect Transmissibility of SARS-COV-2 Variants

The deactivating effects of heat and sunlight on SARS-CoV-2, the virus that causes COVID-19, are consistent across different variants of the virus, according to new research from the Department of Homeland Security (DHS) Science and Technology Directorate (S&T).  This suggests that the increased transmissibility of certain variants is not due to any difference in environmental survivability in aerosols. The research, conducted under S&T’s Probabilistic Analysis for National Threats Hazards and Risks (PANTHR) program, is published in the peer-reviewed scientific Journal of Infectious Diseases.

Key findings:

  • Decay rates of infectious virus are strongly affected by simulated sunlight.
  • Temperature and relative humidity have a smaller influence on decay rate.
  • No differences were observed between isolates without simulated sunlight.
  • A slight difference was observed between some isolates in simulated sunlight.
  • Results suggest decay rates do not vary greatly among currently circulating variants.

“There is still a lot for scientists to learn about SARS-CoV-2, the variants that have emerged, and what contributes to their transmission in the community,” said Dr. Lloyd Hough, lead for S&T’s Hazard Awareness & Characterization Technology Center (HAC-TC).  “But this research shows that the stability of these variants in the environment is about the same, and that the risk assessments and tools that S&T produced early in the pandemic are still applicable.”

Early in the COVID-19 pandemic, the National Biodefense Analysis and Countermeasures Center (NBACC) in Fort Detrick, MD, examined the influence of environmental conditions on the stability of a single isolate of SARS-CoV-2.  As new strains of the virus emerged, NBACC researchers began studying isolates from multiple variants (including one belonging to the recently emerged B.1.1.7 lineage, also known as the UK variant), to determine whether there were differences in stability of the variants in aerosols that might affect their potential for transmission.

The influence of temperature, relative humidity, and simulated sunlight on the isolates in aerosols were compared in an environmentally controlled rotating drum chamber. Aerosols were generated from simulated respiratory tract lining fluid to represent aerosols originating from the deep lung.  The researchers determined that while certain variants may spread faster or be more lethal, they survive similarly in the environment, and therefore differences in transmissibility are likely not due to differences in aerosol stability.

The Fight Goes On

DHS S&T continues its laboratory research to support the battle against COVID-19. Among other efforts, S&T summarizes scientific research from around the world in the Master Questions List (MQL), consolidating what is known about the virus and what additional information is still needed. Highlights of S&T’s response efforts can be found in the Battling the Invisible Enemy report and on S&T’s COVID-19 Research page.

Read more at DHS S&T

Homeland Security Todayhttp://www.hstoday.us
The Government Technology & Services Coalition's Homeland Security Today (HSToday) is the premier news and information resource for the homeland security community, dedicated to elevating the discussions and insights that can support a safe and secure nation. A non-profit magazine and media platform, HSToday provides readers with the whole story, placing facts and comments in context to inform debate and drive realistic solutions to some of the nation’s most vexing security challenges.

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